Pharmacy PEBC Practice Exam

For patients with a previous history of gastric ulcers who require ASA daily for stroke prophylaxis, which of the following is the most effective management strategy?

1. Concurrent use of an H2 antagonist

2. Use of an enteric-coated product

3. Reduce the dose of ASA to every other day

4. Screening and eradication of H. pylori

The correct answer is: Screening and eradication of H. pylori

Patients with a previous history of gastric ulcers who require ASA daily for stroke prophylaxis are at risk for developing another ulcer due to the gastrointestinal side effects of ASA. The most effective management strategy for these patients is to screen for and eradicate H. pylori, a bacteria that is known to cause stomach ulcers. Option A, concurrent use of an H2 antagonist, may temporarily alleviate symptoms but will not prevent the recurrence of gastric ulcers. Option B, use of an enteric-coated product, may also provide temporary relief but does not address the underlying cause of gastric ulcers. Option C, reducing the dose of ASA to every other day, may be an effective strategy but does not address the risk of developing another ulcer from daily ASA use. Therefore, option D, screening and eradication of H. pylori, is the most effective and appropriate management strategy for these patients.