Rock the Pharmacy PEBC Test 2025 – Your Prescription for Success!

PB is a 70 year old female who is on the final day of a 10-day course of cotrimoxazole DS, i po bid for mild pyelonephritis. PB’s medical conditions include hypertension and osteoarthritis, for which she takes enalapril 5 mg po bid and acetaminophen 650 mg po qid. PB has been feeling unwell for the past two days, complaining of abdominal pain, diarrhea, and muscle weakness. She presents to the emergency department, where it is discovered that her serum potassium level is 5.9 mmol/L (normal: 3.5-5.0 mmol/L) and her estimated creatinine clearance is 70 mL/min. One month later, PB returns to her family physician with symptoms of another urinary tract infection (UTI). When hospitalized last month, her urinalysis showed resolution of the original UTI. This is now PB’s third UTI in the past six months. She is still taking enalapril and acetaminophen as before, and she has no known allergies. After resolution of the current infection, which of the following is the most appropriate regimen for UTI prophylaxis for PB?